Evaluation of the disk diffusion method compared to the microdilution method in susceptibility testing of anidulafungin against filamentous fungi

J Clin Microbiol. 2008 Dec;46(12):4071-4. doi: 10.1128/JCM.01088-08. Epub 2008 Oct 15.

Abstract

Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-microg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Anidulafungin
  • Antifungal Agents / pharmacology*
  • Echinocandins / pharmacology*
  • Fungi / drug effects*
  • Humans
  • Microbial Sensitivity Tests / methods*
  • Mycoses / microbiology

Substances

  • Antifungal Agents
  • Echinocandins
  • Anidulafungin