Norcyperone, a novel skeleton norsesquiterpene from Cyperus rotundus L

Molecules. 2008 Oct 10;13(10):2474-81. doi: 10.3390/molecules13102474.

Abstract

A novel norsesquiterpene, named norcyperone (1), and three known compounds: (-)-clovane-2,9-diol (2), rosenonolactone (3), and 5 alpha,8 alpha-epidioxy-(20S,22E,24R)-ergosta-6,22-dien-3beta-ol (4) were isolated from the rhizomes of Cyperus rotundus L. The structure of 1 was elucidated as 8,11,11-trimethylbicyclo[5.3.1]undecane-5 alpha, 8 alpha-epoxy-3-one on the basis of extensive spectroscopic analyses, including 1D- and 2D-NMR, MS experiments, and single-crystal X-ray diffraction. This is the first report of a 8,11,11-trimethyl- bicyclo[5.3.1]undecane-3-one type norsesquiterpene with a tetrahydrofuran ring at C-5 and C-8.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyperus / chemistry*
  • Furans
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Structure
  • Sesquiterpenes / chemistry*
  • X-Ray Diffraction

Substances

  • Furans
  • Sesquiterpenes
  • tetrahydrofuran