Inhaled nitric oxide in the term newborn

Early Hum Dev. 2008 Nov;84(11):709-16. doi: 10.1016/j.earlhumdev.2008.08.002. Epub 2008 Oct 19.


Inhaled nitric oxide is a selective pulmonary vasodilator that serves integral diagnostic and therapeutic roles in the clinical management of near-term and term newborns with hypoxemic respiratory failure and pulmonary hypertension. Its proper use and potential limitations in current clinical practice are reviewed.

Publication types

  • Review

MeSH terms

  • Administration, Inhalation
  • Clinical Trials as Topic
  • Echocardiography
  • Extracorporeal Membrane Oxygenation
  • Humans
  • Infant, Newborn
  • Nitric Oxide / administration & dosage*
  • Persistent Fetal Circulation Syndrome / drug therapy*
  • Vasodilator Agents / administration & dosage*


  • Vasodilator Agents
  • Nitric Oxide