Nutramigen AA is an amino acid-based formula for infants with multiple food protein intolerance or severe cow's milk allergy. Similar growth, tolerance, and safety profiles were found in a study comparing Nutramigen AA with a control formula (Nutramigen LIPIL) in healthy, term, formula-fed infants in a randomised study. Moreover, no allergic reactions were observed in a double-blind, placebo-controlled food challenge in infants or children randomised to receive Nutramigen AA or placebo (Neocate). In conclusion, Nutramigen AA sustains growth and is well tolerated in babies with cow's milk allergy.