Synthesis of functionalised diarylmethanes via a cobalt-catalysed cross-coupling of arylzinc species with benzyl chlorides

Chem Commun (Camb). 2008 Oct 28:(40):5019-21. doi: 10.1039/b809626k. Epub 2008 Sep 2.

Abstract

A new cobalt-catalysed reductive coupling of aryl halides with benzyl chlorides is reported; a variety of diarylmethanes can be prepared in good to excellent yields under mild reaction conditions using CoBr(2) as catalyst and Zn dust; this new cobalt-catalysed coupling represents a practical and interesting alternative to previously known methods for the synthesis diarylmethanes.

MeSH terms

  • Benzyl Compounds / chemistry*
  • Catalysis
  • Cobalt / chemistry*
  • Methane / chemistry*
  • Organometallic Compounds / chemistry*
  • Oxidation-Reduction
  • Zinc / chemistry*

Substances

  • Benzyl Compounds
  • Organometallic Compounds
  • Cobalt
  • benzyl chloride
  • Zinc
  • Methane