[Use of dibunol in pharmacological correction of post-vagotomy hypoxia of digestive organs in rats]

Biull Eksp Biol Med. 1991 Jun;111(6):633-4.
[Article in Russian]


1, 7, 14, 30 and 60 days after bilateral sub-diaphragmatic truncal vagotomy tension of oxygen (pO2) in liver, stomach and small intestine (jejunum) was determined. It was demonstrated that vagotomy leads to a decrease of pO2 in all investigated organs 1 day after the operation (such changes were observed in sham-operated rats) and 30 days, in jejunum--after 7 days, in liver--after 14 days, in stomach--after 60 days. Dibunol introduction in vagotomized rats during 29 days (starting from the second day after operation) results in pO2 normalization in all investigated organs.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Butylated Hydroxytoluene / therapeutic use*
  • Digestive System / metabolism*
  • Gastric Mucosa / metabolism
  • Jejunum / metabolism
  • Liver / metabolism
  • Oxygen Consumption*
  • Rats
  • Time Factors
  • Tissue Distribution
  • Vagotomy, Truncal*


  • Butylated Hydroxytoluene