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, 39 (4), 1041-2

A Cytotoxic Substance From Sangre De Grado

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A Cytotoxic Substance From Sangre De Grado

H Itokawa et al. Chem Pharm Bull (Tokyo).

Abstract

Taspine has been isolated as a cytotoxic substance from Sangre de Grado, sap of Croton palanostigma (Euphorbiaceae), by bioassay guided fractionation. The cytotoxicity (IC50) of taspine was found to be 0.39 microgram/ml against KB cells and 0.17 microgram/ml against V-79 cells.

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