Prolonged survival with isolated levocardia and situs inversus

Cleve Clin J Med. May-Jun 1991;58(3):243-7. doi: 10.3949/ccjm.58.3.243.


Isolated levocardia with situs inversus, or ILSI, is a rare anomaly with a reported incidence of 1:22,000 in the general population and from 0.4% to 1.2% of all patients with congenital heart diseases. It is commonly associated with both congenital heart disease and splenic abnormalities, either asplenia or polysplenia. The prognosis is poor, and only about 5% to 13% of patients survive more than 5 years. The case described here, which had computed tomographic findings, is the first case reported with multiple malignancies associated with ILSI. This patient, at 73 years of age, is the second longest survivor reported in the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abnormalities, Multiple* / diagnosis
  • Abnormalities, Multiple* / mortality
  • Aged
  • Female
  • Humans
  • Levocardia / complications*
  • Levocardia / diagnosis
  • Levocardia / mortality
  • Neoplasms, Multiple Primary / complications*
  • Neoplasms, Multiple Primary / mortality
  • Prognosis
  • Situs Inversus / complications*
  • Situs Inversus / diagnosis
  • Situs Inversus / mortality
  • Survival Rate
  • Tomography, X-Ray Computed