Parallel scan spectral surface plasmon resonance imaging

Appl Opt. 2008 Oct 20;47(30):5616-21. doi: 10.1364/ao.47.005616.

Abstract

We describe a parallel scan spectral surface plasmon resonance (SPR) imaging technique. We demonstrate experimentally, with a line-shaped light illumination, that an image acquired with an area CCD detector provides both SPR wavelength information and one-dimensional spatial distribution. Thus two-dimensional distribution of the refractive index of the entire sensing plane can be obtained with a one-dimensional optical line parallel scan. The technique offers advantages of both high sensitivity and high throughput, and could have potential applications in biochips analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • Glucose
  • Image Processing, Computer-Assisted
  • Microscopy, Polarization
  • Models, Theoretical
  • Refractometry
  • Solutions
  • Surface Plasmon Resonance / instrumentation
  • Surface Plasmon Resonance / methods*

Substances

  • Solutions
  • Glucose