Infantile hemangiomas: an emerging health issue linked to an increased rate of low birth weight infants

J Pediatr. 2008 Nov;153(5):712-5, 715.e1. doi: 10.1016/j.jpeds.2008.05.043.


A total of 420 children with infantile hemangioma (IH) were compared with 353 age-matched controls. Using multivariate logistic regression, low birth weight was the most significant risk factor; for every 500-g decrease in birth weight, the risk of IH increased by 40%. A positive family history also increased the risk of IH (33% vs 15% of controls; P < .001).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Case-Control Studies
  • Cohort Studies
  • Female
  • Hemangioma / diagnosis*
  • Hemangioma / epidemiology*
  • Humans
  • Infant
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Male
  • Maternal Age
  • Odds Ratio
  • Pediatrics / methods
  • Registries
  • Regression Analysis
  • Risk Factors