Alcohol-based hand-disinfection reduced children's absence from Swedish day care centers

Acta Paediatr. 2008 Dec;97(12):1672-80. doi: 10.1111/j.1651-2227.2008.01057.x. Epub 2008 Oct 1.


Aim: To determine if the use of alcohol-based hand-disinfection as a complement to regular hand washing at daycare centers (DCCs) can reduce the childhood rate of absenteeism.

Methods: Children aged 0-6 years attending DCC were studied in a cluster randomized controlled trial during 30 weeks. Thirty matched pairs of DCCs were included in the study, where one of the DCCs was randomized to intervention and the other to control within each pair. The intervention consisted in children and staff using alcohol-based oily disinfectant gel containing 70% ethanol after regular hand washing. The main outcome was the rate of episodes of absence from DCC due to infection. A regression model was fitted at the individual level and controlling several possible confounders for illness. Absences were reported by the parents.

Results: Differences in missing absence reports between the two groups led to only evaluating those 29 DCCs (1431 children) that were able to provide complete reports. In the multivariate regression, the intervention significantly reduced the rate of absenteeism of a child by 12% compared to a child in a control DCC (IRR 95% CI: 0.799-0.965).

Conclusion: Hand-disinfection used by children and staff significantly decreased childrens absences due to infections in Swedish DCCs.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absenteeism*
  • Alcohols / therapeutic use
  • Child
  • Child Day Care Centers / methods*
  • Child, Preschool
  • Cluster Analysis
  • Disinfection / methods*
  • Female
  • Gels / therapeutic use
  • Hand Disinfection / methods*
  • Humans
  • Infant
  • Infant, Newborn
  • Logistic Models
  • Male
  • Sweden


  • Alcohols
  • Gels