Thoracic chordoma: review and role of FDG-PET

J Neurosurg Sci. 2008 Dec;52(4):117-21; discussion 121-2. Epub 2008 Oct 23.

Abstract

Chordoma is an uncommon primary bone tumor and the thoracic spine is the least common of all sites for a chordoma. It may recur despite slow-growing nature. Precise literature review will be performed and possible use of fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) for detection of both primary and recurrent diagnosis will be discussed. This article presents the case of a 73-year-old male patient who complained of back pain. Magnetic resonance (MR) imaging, computed tomography (CT) and FDG-PET demonstrated thoracic lesion and biopsy revealed chordoma. The patient was operated on and histological findings showed the tumor was chondroid chordoma. He suffered recurrence after 7 months by FDG-PET. He received 6,000 rads radiation therapy and is neurological free but, suffered backache 15 months after initial diagnosis. Only 12 cases including this case were reported precisely and this is the first report of FDG-PET for both initial and recurrent diagnosis of chordoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Back Pain / etiology
  • Biopsy
  • Chordoma / diagnostic imaging*
  • Chordoma / pathology
  • Chordoma / therapy
  • Diagnosis, Differential
  • Diagnostic Errors / prevention & control
  • Fluorodeoxyglucose F18*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neoplasm Recurrence, Local / radiotherapy
  • Neurosurgical Procedures
  • Positron-Emission Tomography*
  • Predictive Value of Tests
  • Spinal Neoplasms / diagnostic imaging*
  • Spinal Neoplasms / pathology
  • Spinal Neoplasms / therapy
  • Thoracic Vertebrae / diagnostic imaging*
  • Thoracic Vertebrae / pathology
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Fluorodeoxyglucose F18