Primary obstructive megaureter

J Pediatr Surg. 1991 Jul;26(7):826-9. doi: 10.1016/0022-3468(91)90148-m.

Abstract

Twenty-three children with primary obstructive megaureters presented between 1978 and 1988 to the Princess Margaret Hospital for Children in Perth. Twenty-eight ureters were treated. Urinary infections were the presenting feature in 14 children. The obstructive segment was transvesically excised. Histopathologic examination of the distal, intramural ureter showed fibromuscular disarray with a relative increase in fibrous tissue and reduction of musculature in all specimens. Twenty-two ureters were tapered by excision and all 28 were reimplanted using an antireflux technique. Seventeen children were followed for an average of 3 years. Seven children showed renal growth, reduction in ureteric size by greater than 2 cm, improvement in glomerular filtration rate by more than 10%, no obstruction on reflux, and no infections in postoperative period. Four children showed all the above but suffered one or more infections after the operation. Of the remaining 6 children, 3 had postoperative obstruction and 3 had vesicoureteric reflux.

MeSH terms

  • Child
  • Child, Preschool
  • Drainage
  • Escherichia coli Infections / diagnosis
  • Escherichia coli Infections / etiology*
  • Escherichia coli Infections / surgery
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Nephrostomy, Percutaneous
  • Pyelonephritis / diagnosis
  • Pyelonephritis / etiology*
  • Pyelonephritis / surgery
  • Replantation
  • Ureter / abnormalities*
  • Ureter / pathology
  • Ureter / surgery
  • Ureteral Obstruction / diagnosis
  • Ureteral Obstruction / etiology*
  • Ureteral Obstruction / surgery