The complete genome sequence of Bacillus anthracis Ames "Ancestor"

J Bacteriol. 2009 Jan;191(1):445-6. doi: 10.1128/JB.01347-08. Epub 2008 Oct 24.


The pathogenic bacterium Bacillus anthracis has become the subject of intense study as a result of its use in a bioterrorism attack in the United States in September and October 2001. Previous studies suggested that B. anthracis Ames Ancestor, the original Ames fully virulent plasmid-containing isolate, was the ideal reference. This study describes the complete genome sequence of that original isolate, derived from a sample kept in cold storage since 1981.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Bacillus anthracis / genetics*
  • Bacillus anthracis / isolation & purification
  • Bacillus anthracis / pathogenicity
  • Chromosomes, Bacterial / genetics
  • Evolution, Molecular*
  • Female
  • Genome, Bacterial*
  • Horses / microbiology
  • Plasmids
  • Virulence