Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 135 (22), 3625-41

Regulated Adhesion as a Driving Force of Gastrulation Movements

Affiliations
Review

Regulated Adhesion as a Driving Force of Gastrulation Movements

Matthias Hammerschmidt et al. Development.

Abstract

Recent data have reinforced the fundamental role of regulated cell adhesion as a force that drives morphogenesis during gastrulation. As we discuss, cell adhesion is required for all modes of gastrulation movements in all organisms. It can even be instructive in nature, but it must be tightly and dynamically regulated. The picture that emerges from the recent findings that we review here is that different modes of gastrulation movements use the same principles of adhesion regulation, while adhesion molecules themselves coordinate the intra- and extracellular changes required for directed cell locomotion.

Similar articles

See all similar articles

Cited by 33 PubMed Central articles

See all "Cited by" articles

Substances

LinkOut - more resources

Feedback