An investigation of the effects of saccharides on the memory performance of middle-aged adults

J Nutr Health Aging. 2008 Nov;12(9):657-62. doi: 10.1007/BF03008278.


Objectives: To investigate the effects of glucose, or a combination of saccharides, or a placebo on the memory performance of middle-aged adults.

Design: A double-blind, placebo controlled design was used. A population-based sample of 45 men and women (aged 40-63 years) completed a series of memory tasks following administration of a single dose of either glucose, a combination of saccharides or placebo. Memory tasks included immediate and delayed recall, recognition, short-term memory, working memory, and a test of general cognitive ability.

Results: There were no statistically significant effects of treatments on any of the outcome measures.

Conclusion: The pattern of means in the combination of saccharides group suggests potential enhancement effects of memory performance in middle-aged adults that deserves further investigation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Cognition / drug effects*
  • Cognition / physiology
  • Dietary Carbohydrates / pharmacology*
  • Double-Blind Method
  • Female
  • Glucose / pharmacology*
  • Humans
  • Male
  • Memory / drug effects*
  • Memory / physiology
  • Mental Recall
  • Middle Aged


  • Dietary Carbohydrates
  • Glucose