Selectome: a database of positive selection

Nucleic Acids Res. 2009 Jan;37(Database issue):D404-7. doi: 10.1093/nar/gkn768. Epub 2008 Oct 28.


Genome wide scans have shown that positive selection is relatively frequent at the molecular level. It is of special interest to identify which protein sites and which phylogenetic branches are affected. We present Selectome, a database which provides the results of a rigorous branch-site specific likelihood test for positive selection. The Web interface presents test results mapped both onto phylogenetic trees and onto protein alignments. It allows rapid access to results by keyword, gene name, or taxonomy based queries. Selectome is freely available at

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Genetic*
  • Genes*
  • Phylogeny
  • Proteins / classification
  • Proteins / genetics*
  • Selection, Genetic*
  • Sequence Homology, Amino Acid
  • User-Computer Interface


  • Proteins