tRNAdb 2009: compilation of tRNA sequences and tRNA genes

Nucleic Acids Res. 2009 Jan;37(Database issue):D159-62. doi: 10.1093/nar/gkn772. Epub 2008 Oct 28.


One of the first specialized collections of nucleic acid sequences in life sciences was the 'compilation of tRNA sequences and sequences of tRNA genes' ( Here, an updated and completely restructured version of this compilation is presented ( The new database, tRNAdb, is hosted and maintained in cooperation between the universities of Leipzig, Marburg, and Strasbourg. Reimplemented as a relational database, tRNAdb will be updated periodically and is searchable in a highly flexible and user-friendly way. Currently, it contains more than 12 000 tRNA genes, classified into families according to amino acid specificity. Furthermore, the implementation of the NCBI taxonomy tree facilitates phylogeny-related queries. The database provides various services including graphical representations of tRNA secondary structures, a customizable output of aligned or un-aligned sequences with a variety of individual and combinable search criteria, as well as the construction of consensus sequences for any selected set of tRNAs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Nucleic Acid*
  • Phylogeny
  • RNA, Transfer / chemistry*
  • RNA, Transfer / classification
  • RNA, Transfer / genetics*
  • Sequence Analysis, DNA
  • Sequence Analysis, RNA
  • Software


  • RNA, Transfer