A glassy-carbon electrode modified by dispersed alpha-alumina as an enhanced electrochemical detector in liquid chromatography for cysteine and glutathione

W Hou; E Wang

doi:10.1016/0039-9140(91)80180-8

A glassy-carbon electrode modified by dispersed alpha-alumina as an enhanced electrochemical detector in liquid chromatography for cysteine and glutathione

Talanta. 1991 May;38(5):557-60. doi: 10.1016/0039-9140(91)80180-8.

Authors

W Hou¹, E Wang

Affiliation

¹ Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, People's Republic of China.

PMID: 18965187
DOI: 10.1016/0039-9140(91)80180-8

Abstract

The dispersion of alumina particles on a glassy-carbon surface serving as a modified electrode significantly enhances the amperometric detection of cysteine and glutathione following liquid chromatography. With an applied potential of 0.8 V vs. SCE, the detection limits were 1.2 ng for cysteine and 8 ng for glutathione and the electrode response was linear up to 600 ng for cysteine and 1.8 mug for glutathione. The modified electrode displayed high sensitivity and stability and was easy and inexpensive to prepare.