Study of antioxidant properties of a water-soluble Vitamin E derivative-tocopherol monoglucoside (TMG) by differential pulse voltammetry

E I Korotkova; O A Avramchik; T V Kagiya; Y A Karbainov; N V Tcherdyntseva

doi:10.1016/j.talanta.2003.12.030

Study of antioxidant properties of a water-soluble Vitamin E derivative-tocopherol monoglucoside (TMG) by differential pulse voltammetry

Talanta. 2004 Jun 17;63(3):729-34. doi: 10.1016/j.talanta.2003.12.030.

Authors

E I Korotkova¹, O A Avramchik, T V Kagiya, Y A Karbainov, N V Tcherdyntseva

Affiliation

¹ Department of Physical and Analytical Chemistry, Tomsk Polytechnic University, Lenin 30, Tomsk, Russia.

PMID: 18969493
DOI: 10.1016/j.talanta.2003.12.030

Abstract

Study of antioxidant properties of tocopherol monoglucoside (TMG), a water-soluble Vitamin E derivative, by differential pulse voltammetry has been carried out in this work. The pH influence on the antioxidant properties of TMG has been also investigated. It was observed that the antioxidant activity of TMG is greater at 6.90<pH<9.18. The reactions between the TMG and reactive oxygen species have been considered. Antioxidant activity of some standard antioxidants including Vitamin E was given for comparison. The results indicate that the TMG is an effective antioxidant in neutral solutions. The oxidation potential for TMG at pH 7.31 has been found (E=0.55+/-0.03V versus Ag|AgCl|KCl(sat) electrode). Finally the use of TMG for protection against oxidative stress has been recommended.