[Satisfaction and compliance of ocular hypertensive and glaucoma patients topically treated with a combination therapy]

J Fr Ophtalmol. 2008 Sep;31(7):659-65. doi: 10.1016/s0181-5512(08)74379-1.
[Article in French]

Abstract

Objectives: To evaluate satisfaction and compliance in glaucoma and ocular hypertensive patients receiving a fixed combination treatment.

Materials and methods: After instilling a fixed combination, patients were asked to fill out a questionnaire about their satisfaction and compliance at baseline and 15 days after the onset of new therapy.

Results: 1693 glaucoma patients (G) and 621 ocular hypertensive (OHT) patients were included. Mean age was 65.6+/-11.7 years. Onset of disease was 7.2+/-6.6 years and 5.2+/-4.9 years for G and OHT patients, respectively. Insufficient efficacy of the previous topical treatment (monotherapy in 55% of cases) was the main cause for shifting to a fixed combination in 70% of cases. Satisfaction was increased in 15% of the patients and compliance was increased in 25% of the patients.

Discussion: Fixed combination provides an easier regimen and therefore encourages better compliance, a key issue in a chronic disease such as glaucoma.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Multicenter Study

MeSH terms

  • Adrenergic beta-Antagonists / administration & dosage*
  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Carbonic Anhydrase Inhibitors / administration & dosage*
  • Carbonic Anhydrase Inhibitors / therapeutic use
  • Drug Combinations
  • Female
  • Glaucoma, Open-Angle / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Ocular Hypertension / drug therapy*
  • Ophthalmic Solutions
  • Patient Compliance*
  • Patient Satisfaction*
  • Prospective Studies
  • Prostaglandins / administration & dosage*
  • Prostaglandins / therapeutic use
  • Treatment Outcome

Substances

  • Adrenergic beta-Antagonists
  • Carbonic Anhydrase Inhibitors
  • Drug Combinations
  • Ophthalmic Solutions
  • Prostaglandins