Heavy silicone oil tamponade after failed macular hole surgery with perfluoropropane (C3F8): a report of five cases

Graefes Arch Clin Exp Ophthalmol. 2009 May;247(5):707-9. doi: 10.1007/s00417-008-0965-6. Epub 2008 Oct 30.


We report five cases of persistent macular holes following conventional surgery. Subsequent management included pars plana vitrectomy, extended Trypan Blue-assisted ILM peel and heavy silicone oil (HSO) tamponade with supine posture.

Purpose: To report results of redo macular hole surgery using heavy silicone oil (HSO) tamponade.

Methods: Retrospective study of patients with primary failure of macular hole surgery, who failed to posture prone due to medical reasons. Further surgery consisted of vitrectomy, extended-dye-assisted ILM peel, and HSO tamponade with supine posture.

Results: Anatomical closure of macular holes was achieved in three out of five cases with parallel improvement in visual acuity after 3 months of removal of heavy silicone oil. These were confirmed clinically and by ocular coherence tomography (OCT).

Conclusions: HSO may be used as tamponade in patients with unsuccessful primary macular-hole surgery, negating the need of prone posturing post-operatively.

MeSH terms

  • Basement Membrane / pathology
  • Basement Membrane / surgery
  • Coloring Agents
  • Drainage / methods
  • Fluorocarbons / administration & dosage*
  • Humans
  • Recurrence
  • Retinal Perforations / diagnosis
  • Retinal Perforations / physiopathology
  • Retinal Perforations / therapy*
  • Retrospective Studies
  • Silicone Oils / administration & dosage*
  • Supine Position
  • Tomography, Optical Coherence
  • Treatment Failure
  • Treatment Outcome
  • Trypan Blue
  • Visual Acuity / physiology
  • Vitrectomy*


  • Coloring Agents
  • Fluorocarbons
  • Silicone Oils
  • densiron
  • perflutren
  • Trypan Blue