Comparison between Bricanyl Turbuhaler and Ventolin metered dose inhaler in the treatment of exercise-induced asthma in adults

Ann Allergy. 1991 Sep;67(3):315-8.


The aim of the present study was to compare the effect of Bricanyl Turbuhaler (0.5 mg x 1 terbutaline) with the effect of albuterol metered dose inhaler (0.1 mg x 2 albuterol) in patients with reproducible bronchoconstriction. The study was performed as a double-blind placebo-controlled trial in sixteen asthmatic adults. Bronchoconstriction was induced by steady state running on a treadmill. Both 0.5 mg terbutaline and 0.2 mg albuterol have good bronchodilating effects in patients with exercise-induced asthma. There was, however, a faster onset of action after albuterol. The clinical value of this observed difference is uncertain.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Adult
  • Albuterol / administration & dosage*
  • Asthma, Exercise-Induced / drug therapy*
  • Double-Blind Method
  • Heart Rate
  • Humans
  • Middle Aged
  • Nebulizers and Vaporizers / statistics & numerical data*
  • Peak Expiratory Flow Rate
  • Placebos
  • Terbutaline / administration & dosage*


  • Placebos
  • Terbutaline
  • Albuterol