Exercise-induced collapse of Labrador retrievers: survey results and preliminary investigation of heritability

J Am Anim Hosp Assoc. 2008 Nov-Dec;44(6):295-301. doi: 10.5326/0440295.


Completed surveys were obtained from owners of 225 Labrador retrievers affected by the syndrome of exercise-induced collapse. Questions addressed signalment, age of onset, description of collapse episodes, and owner perception of activities and factors associated with collapse. Most dogs were young (mean 12 months) when collapse episodes began. Retrieving was the activity most commonly associated with collapse. Owners felt that excitement (187/225; 83%) and high environmental temperatures (71/225; 31%) increased the likelihood of collapse. Analysis of pedigrees collected from 169 affected dogs was most consistent with an autosomal recessive mode of inheritance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Dog Diseases / genetics*
  • Dog Diseases / pathology
  • Dogs
  • Female
  • Genes, Recessive*
  • Genetic Linkage
  • Genetic Predisposition to Disease
  • Male
  • Pedigree*
  • Physical Conditioning, Animal / adverse effects*
  • Syndrome
  • Temperature