Clinical application of tobramycin-impregnated calcium sulfate beads in six dogs (2002-2004)

J Am Anim Hosp Assoc. Nov-Dec 2008;44(6):320-6. doi: 10.5326/0440320.


Medical records for six dogs treated with tobramycin-impregnated calcium sulfate beads were reviewed for indications, duration of disease, number of beads implanted, complications, radiographic appearance of the beads, and outcomes. Beads were no longer visible on radiographs made 5 weeks after implantation. Osteomyelitis resolved in five of five dogs with follow-up. The lack of complications and the resolution of clinical signs associated with tobramycin calcium sulfate bead implantation support their clinical application in treating osteomyelitis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use*
  • Calcium Sulfate / chemistry
  • Dog Diseases / drug therapy*
  • Dogs
  • Drug Delivery Systems / veterinary
  • Female
  • Male
  • Microspheres
  • Osteomyelitis / drug therapy
  • Osteomyelitis / veterinary*
  • Time Factors
  • Tobramycin / therapeutic use*
  • Treatment Outcome


  • Anti-Bacterial Agents
  • Tobramycin
  • Calcium Sulfate