Cardiac surgery and sickle cell disease

Asian Cardiovasc Thorac Ann. 2008 Dec;16(6):479-82. doi: 10.1177/021849230801600610.

Abstract

Three patients with homozygous sickle cell disease underwent successful open heart surgery for multivalvular lesions. Details of the surgical technique and the necessary precautions are described. Exchange transfusion was implemented in all cases. Crucial issues in cardiac surgical management to avoid or at least minimize vasoocclusive crisis and associated complications are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / surgery
  • Anticoagulants / therapeutic use
  • Blood Transfusion
  • Cardiopulmonary Bypass
  • Female
  • Heart Arrest, Induced
  • Heart Valve Diseases / complications
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation* / adverse effects
  • Heart Valve Prosthesis Implantation* / instrumentation
  • Hemofiltration
  • Humans
  • Male
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Prosthesis Design
  • Rheumatic Heart Disease / complications
  • Rheumatic Heart Disease / surgery*
  • Treatment Outcome

Substances

  • Anticoagulants