A bromocoumarin-based linker for synthesis of photocleavable peptidoconjugates with high photosensitivity

Kentaro Katayama; Shinya Tsukiji; Toshiaki Furuta; Teruyuki Nagamune

doi:10.1039/b812058g

A bromocoumarin-based linker for synthesis of photocleavable peptidoconjugates with high photosensitivity

Chem Commun (Camb). 2008 Nov 14:(42):5399-401. doi: 10.1039/b812058g. Epub 2008 Sep 19.

Authors

Kentaro Katayama¹, Shinya Tsukiji, Toshiaki Furuta, Teruyuki Nagamune

Affiliation

¹ Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.

PMID: 18985223
DOI: 10.1039/b812058g

Abstract

A new bromocoumarin-based bi-functional linker was developed for preparing photocleavable peptides and proteins with high photolytic efficiency, which have many potential applications in the study and engineering of biological systems.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Coumarins / chemical synthesis
Coumarins / chemistry*
Ligands
Molecular Structure
Peptides / chemical synthesis*
Peptides / chemistry
Photochemistry

Substances

Coumarins
Ligands
Peptides