Validation of the Glasgow Meningococcal Septicemia Prognostic Score: a 10-year retrospective survey

Crit Care Med. 1991 Jan;19(1):26-30. doi: 10.1097/00003246-199101000-00010.


Objective: To derive performance characteristics for the Glasgow Meningococcal Septicemia Prognostic Score (GMSPS).

Design: Retrospective case-note study.

Setting: Two children's hospitals with Regional Intensive Care Unit.

Patients: One hundred twenty-three children with proven meningococcal septicemia (some with concurrent meningitis) from January 1, 1977 to December 31, 1986.

Measurements and main results: All 14 children who died after arrival scored greater than or equal to 8 either on admission (n = 8) or afterward (n = 6). Of 109 survivors, five scored greater than or equal to 8 (two were postictal at the time of scoring). A GMSPS of greater than or equal to 10 at or after admission predicted death with sensitivity 100%, specificity 98%, and positive predictive value of 88%; for GMSPS of both greater than or equal to 8 or 9, the values were 100%, 95%, and 74%, respectively.

Conclusions: The GMSPS is a rapid clinical score that performs well in identifying children with poor prognosis who might benefit from early intensive care. It should be studied prospectively and compared with other scoring systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Meningococcal Infections / diagnosis*
  • Neisseria meningitidis*
  • Predictive Value of Tests
  • Prognosis
  • Retrospective Studies
  • Sensitivity and Specificity
  • Sepsis / diagnosis*
  • Severity of Illness Index*