Case report and literature review: acute pneumonitis and alveolar hemorrhage after subcutaneous injection of liquid silicone

Ann Clin Lab Sci. 2008 Autumn;38(4):380-5.


Lay (non-medical) injection of silicone may lead to serious clinical consequences. Most reports of illicit cosmetic procedures have dealt with failed, lay attempts at breast augmentation. Although these procedures have resulted in severe pneumonitis and alveolar hemorrhage, reports of similar complication after lay attempts at buttock augmentation have been sparse. We describe one of these rare cases and review the literature on clinicopathologic sequelae of lay attempts at cosmetic procedures using commercially available silicone preparations.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Female
  • Hemorrhage / chemically induced*
  • Hemorrhage / complications
  • Hemorrhage / pathology
  • Humans
  • Injections, Subcutaneous
  • Mammaplasty / adverse effects
  • Pneumonia / chemically induced*
  • Pneumonia / complications
  • Pneumonia / pathology
  • Pulmonary Alveoli / pathology*
  • Pulmonary Embolism / chemically induced*
  • Pulmonary Embolism / complications
  • Pulmonary Embolism / pathology
  • Silicones / administration & dosage
  • Silicones / adverse effects*


  • Silicones