Maximum aortic diameter as a simple predictor of acute type B aortic dissection

Ann Thorac Cardiovasc Surg. 2008 Oct;14(5):303-10.

Abstract

Objectives: To identify the most prognostic predictor of Stanford type B aortic dissection at admission.

Patients and methods: Forty-three patients with Stanford type B aortic dissection were divided into two groups: (1) those who developed dissection-related events later (EV group: n = 18), including the need for surgery (n = 12), rupture (n = 1), dissection-related death (n = 5), and aortic enlargement > or =5 mm in diameter per year (n = 15); (2) those without later events (NoEV group: n = 25). Clinical features, aortic diameters, and blood flow status were compared.

Results: The maximum aortic diameter at admission was 41.5 +/- 1.7 mm for the EV group, which was significantly greater than the NoEV group (34.4 +/- 0.9 mm, p <0.001). A maximum aortic diameter > or =40 mm was found in 11 patients (61%) of the EV group, whereas this maximum was found in 4 (16%) of the NoEV group (p = 0.004). A patent false lumen at admission was found in all patients of the EV group and in 17 (68%) of the NoEV group (p = 0.013). Other factors were not significant. A Cox hazard analysis indicated a maximum aortic diameter > or =40 mm as a significant predictor for dissection-related events (hazard ratio 3.13, p = 0.032). The presence of a patent false lumen did not reach a statistical significance.

Conclusion: Our results indicated that a maximum aortic diameter > or =40 mm at admission was the most prognostic factor for developing late dissection-related events, rather than the presence of a patent false lumen.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography, Digital Subtraction
  • Aorta / pathology*
  • Aorta / physiopathology
  • Aorta / surgery
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / pathology*
  • Aortic Aneurysm / physiopathology
  • Aortic Aneurysm / surgery
  • Aortic Dissection / mortality
  • Aortic Dissection / pathology*
  • Aortic Dissection / physiopathology
  • Aortic Dissection / surgery
  • Aortic Rupture / mortality
  • Aortic Rupture / pathology*
  • Aortic Rupture / physiopathology
  • Aortic Rupture / surgery
  • Aortography
  • Disease-Free Survival
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Proportional Hazards Models
  • Regional Blood Flow
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Severity of Illness Index
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vascular Surgical Procedures / adverse effects