Cortical imaging of event-related (de)synchronization during online control of brain-computer interface using minimum-norm estimates in frequency domain

IEEE Trans Neural Syst Rehabil Eng. 2008 Oct;16(5):425-31. doi: 10.1109/TNSRE.2008.2003384.


It is of wide interest to study the brain activity that correlates to the control of brain-computer interface (BCI). In the present study, we have developed an approach to image the cortical rhythmic modulation associated with motor imagery using minimum-norm estimates in the frequency domain (MNEFD). The distribution of cortical sources of mu activity during online control of BCI was obtained with the MNEFD. Contralateral decrease (event-related desynchronization) and ipsilateral increase (event-related synchronization) are localized in the sensorimotor cortex during online control of BCI in a group of human subjects. Statistical source analysis revealed that maximum correlation with movement imagination is localized in sensorimotor cortex.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms*
  • Brain Mapping / methods*
  • Electroencephalography / methods*
  • Evoked Potentials, Motor / physiology*
  • Humans
  • Imagination / physiology*
  • Male
  • Motor Cortex / physiology*
  • Movement / physiology*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • User-Computer Interface*
  • Young Adult