Ann N Y Acad Sci. 2008 Oct:1139:402-11. doi: 10.1196/annals.1432.003.


Dextromethorphan is reviewed in its role as an emerging drug of abuse, and the effects of dextromethorphan, along with those of co-ingredients in OTC formulations, are discussed. The Drug Abuse and Warning Network (DAWN) national data in the United States are examined in the context of data from other poison control centers, and possible national trends are postulated. Implications for dextromethorphan as an emerging drug of abuse are explored. Data from the Arkansas Poison Control Center (APCC) show emerging trends in the abuse of dextromethorphan, particularly in this rural area of the United States.

MeSH terms

  • Adolescent
  • Adult
  • Antitussive Agents*
  • Arkansas
  • Child
  • Databases, Factual
  • Dextromethorphan*
  • Drug and Narcotic Control
  • Excitatory Amino Acid Antagonists*
  • Female
  • Humans
  • Illicit Drugs
  • Male
  • Poison Control Centers
  • Retrospective Studies
  • Substance-Related Disorders*


  • Antitussive Agents
  • Excitatory Amino Acid Antagonists
  • Illicit Drugs
  • Dextromethorphan