Primary sclerosing cholangitis

Surg Clin North Am. 2008 Dec;88(6):1385-407, x. doi: 10.1016/j.suc.2008.07.010.


Primary sclerosing cholangitis (PSC) is a generally progressive, sometimes fatal chronic hepatobiliary disorder for which no effective medical therapy now exists. This article describes the epidemiology of this disease, along with diagnosis and treatment options. Future research directions concerning PSC also are discussed.

Publication types

  • Review

MeSH terms

  • Cholangitis, Sclerosing* / diagnosis
  • Cholangitis, Sclerosing* / epidemiology
  • Cholangitis, Sclerosing* / surgery
  • Diagnosis, Differential
  • Diagnostic Techniques, Digestive System
  • Digestive System Surgical Procedures / methods*
  • Global Health
  • Humans
  • Morbidity / trends