Adverse events after anthrax vaccination reported to the Vaccine Adverse Event Reporting System (VAERS), 1990-2007

Vaccine. 2009 Jan 7;27(2):290-7. doi: 10.1016/j.vaccine.2008.10.044. Epub 2008 Nov 6.


During the period March 1, 1998 to January 14, 2007, approximately 6 million doses of Anthrax vaccine adsorbed (AVA) vaccine were administered. As of January 16, 2007, 4753 reports of adverse events following receipt of AVA vaccination had been submitted to the Vaccine Adverse Event Reporting System (VAERS). Taken together, reports to VAERS did not definitively link any serious unexpected risk to this vaccine, and review of death and serious reports did not show a distinctive pattern indicative of a causal relationship to AVA vaccination. Continued monitoring of VAERS and analysis of potential associations between AVA vaccination and rare, serious events is warranted.

MeSH terms

  • Adult
  • Adverse Drug Reaction Reporting Systems / statistics & numerical data*
  • Anthrax / prevention & control*
  • Anthrax Vaccines / adverse effects*
  • Bayes Theorem
  • Drug-Related Side Effects and Adverse Reactions*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Product Surveillance, Postmarketing
  • United States
  • Vaccination / adverse effects
  • Vaccines / adverse effects*
  • Young Adult


  • Anthrax Vaccines
  • Vaccines