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, 16 (11), 1599-600

Enzyme Function Discovery

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Enzyme Function Discovery

Debra Dunaway-Mariano. Structure.

Abstract

The search for an effective method for accurate, automated enzyme-functional annotation of protein sequences of unknown function is, in the minds of many, a Grail quest. Computational chemists, structural biologists, and mechanistic enzymologists now have teamed together to formulate an integrated, stepwise approach to enzyme function annotation (Kalyanaraman et al., 2008).

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