Accuracy of biometry in pediatric cataract extraction with primary intraocular lens implantation

J Cataract Refract Surg. 2008 Nov;34(11):1940-7. doi: 10.1016/j.jcrs.2008.07.019.


Purpose: To determine the accuracy of predicted postoperative refractive outcomes in pediatric patients having cataract surgery with intraocular lens (IOL) implantation and to compare them with other variables historically considered important in cataract surgery.

Setting: Tertiary care referral hospital.

Methods: This retrospective review comprised 203 eyes of 153 consecutive pediatric patients (< or = 18 years old) having cataract extraction with primary posterior chamber IOL implantation in the capsular bag. All cases were performed by 1 of 2 surgeons, and all refractions were performed manually by an experienced pediatric ophthalmologist using a retinoscope.

Results: In all patients, the mean absolute value (MAE) of the prediction error was 1.08 diopters (D) +/- 0.93 (SD). Age at time of surgery and corneal (K) mean curvature were significantly correlated with the absolute value of the prediction error (P = .0006 and P = .0088, respectively). A multiple regression model showed that age at time of surgery and K mean curvature were the only 2 variables significantly associated with MAE; axial length, formula, surgeon, and A-scan type were not significantly associated with prediction error.

Conclusions: Data from 203 consecutive primary pediatric IOL implantations showed the heterogeneous nature of the variables involved in predictions of refractive outcomes in this population. The complexities of this issue support the need for specific methods of measurement and an IOL calculation formula for the pediatric population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Biometry*
  • Cataract Extraction*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Lens Implantation, Intraocular*
  • Male
  • Pseudophakia / physiopathology*
  • Refraction, Ocular / physiology*
  • Reproducibility of Results
  • Retrospective Studies
  • Treatment Outcome