Spontaneous epidural hematoma due to skull metastasis of hepatocellular carcinoma

J Clin Neurosci. 2009 Jan;16(1):137-40. doi: 10.1016/j.jocn.2008.02.020. Epub 2008 Nov 14.


Although "spontaneous" epidural hematomas are rare, they can occur in patients with metastatic skull tumors. We describe a case caused by skull metastasis of hepatocellular carcinoma (HCC), and review the relevant literature. In patients with HCC, potential skull metastasis should be kept in mind, since skull metastases from HCC seem to often cause devastating epidural hematoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Carcinoma, Hepatocellular / pathology*
  • Hematoma, Epidural, Cranial / etiology*
  • Humans
  • Male
  • Middle Aged
  • Skull Neoplasms / complications*
  • Skull Neoplasms / secondary*
  • Tomography, X-Ray Computed / methods