Selection of oligonucleotides for whole-genome microarrays with semi-automatic update

Bioinformatics. 2009 Jan 1;25(1):128-9. doi: 10.1093/bioinformatics/btn573. Epub 2008 Nov 10.

Abstract

Oligonucleotide microarray probes are designed to match specific transcripts present in databases that are regularly updated. As a consequence probes should be checked every new database release. We thus developed an informatics tool allowing the semi-automatic update of probe collections of long oligonucleotides and applied it to the mouse RefSeq database.

Availability: http://www.bio.espci.fr/sol/

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Automation*
  • Computational Biology / methods*
  • Databases, Nucleic Acid
  • Genome / genetics*
  • Oligonucleotide Array Sequence Analysis*
  • Oligonucleotides / genetics*
  • User-Computer Interface

Substances

  • Oligonucleotides