Predictors of quality of life in breast cancer patients under chemotherapy

Indian J Cancer. 2008 Jul-Sep;45(3):107-11. doi: 10.4103/0019-509x.44066.


Background: Today, the quality of life studies has an important role in health care especially in chronic diseases. Breast cancer has third order among women's malignancies. Now, survival rate for this cancer is long. However breast cancer has several complications that affected the patient's life.

Aims: The aim of this study was to assess the quality of life in Breast cancer patients under chemotherapy.

Setting and design: A cross-sectional study conducted on 119 breast cancer patients that were admitted and treated in chemotherapy ward of Namazi hospital in Shiraz city, south of Iran, between Jan and Feb 2006.

Materials and methods: The QLQ-C30 questionnaire was used to assess quality of life in these patients.

Statistical analysis: We used univariate methods. A multiple regression analysis was performed to identify predictors of quality of life.

Results: Mean age of patients was 48.27+/-11.42 with quality of life total score 64.92+/-24.28. All symptoms scales had reverse association with quality of life except appetite loss (P>0.05) and diarrhea (P=0.752). The results of the regression analyses showed that only grade of tumor, occupational status, menopausal status, financial difficulties and dyspnea were statistically significant in predicting patients' quality of life.

Conclusion: In conclusion, this study demonstrates the strength of the relationship between clinical and sociodemographical factors and breast cancer patients' quality of life. Psychological and financial support for women experiencing breast cancer diagnosis may improve quality of life.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / epidemiology
  • Chemotherapy, Adjuvant
  • Cross-Sectional Studies
  • Female
  • Humans
  • Iran / epidemiology
  • Middle Aged
  • Predictive Value of Tests
  • Quality of Life*
  • Surveys and Questionnaires