The human aldose reductase gene maps to chromosome region 7q35

Hum Genet. 1991 Mar;86(5):509-14. doi: 10.1007/BF00194644.


The human aldose reductase (AR) gene has been mapped to chromosome 7 using the polymerase chain reaction to specifically amplify the human AR sequence in hamster/human hybrid DNA and also in mouse/human monochromosome hybrids. The assignment to chromosome 7 was confirmed by in situ hybridisation to human metaphase chromosomes using a novel, rapid hybridisation, method giving a regional localisation at 7q35.

MeSH terms

  • Aldehyde Reductase / genetics*
  • Animals
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 7*
  • Cosmids
  • Cricetinae
  • DNA
  • Humans
  • Hybrid Cells
  • Introns
  • Mice
  • Molecular Sequence Data
  • Nucleic Acid Hybridization
  • Polymerase Chain Reaction


  • DNA
  • Aldehyde Reductase