Thermal lensing in ocular media exposed to continuous-wave near-infrared radiation: the 1150-1350-nm region

J Biomed Opt. 2008 Sep-Oct;13(5):054005. doi: 10.1117/1.2978066.


Ocular damage threshold data remain sparse in the continuous wave (CW), near-infrared (NIR) radiation region save for the 1300-nm area that has been investigated in the past several decades. The 1300-nm ocular damage data have yielded unusual characteristics where CW retinal damage was observed in rabbit models, but never in nonhuman primate models. This paper reviews the existing 1300-nm ocular damage threshold data in terms of the fundamental criteria of an action spectrum to assist in explaining laser-tissue effects from near-infrared radiation in the eye. Reviewing the action spectrum criteria and existing NIR retinal lesion data lend evidence toward the significant presence of thermal lensing in ocular media affecting damage, a relatively unexplored mechanism of laser-tissue interaction.

Publication types

  • Review

MeSH terms

  • Animals
  • Eye Burns / etiology*
  • Eye Burns / physiopathology*
  • Humans
  • Infrared Rays / adverse effects*
  • Lenses
  • Models, Biological*
  • Radiation Dosage
  • Radiation Injuries / etiology*
  • Radiation Injuries / physiopathology*
  • Retina / injuries*
  • Retina / physiopathology*