Rheolytic thrombectomy for dural venous sinus thrombosis

J Neuroimaging. 2009 Oct;19(4):366-9. doi: 10.1111/j.1552-6569.2008.00311.x. Epub 2008 Oct 21.


Background and purpose: Cerebral venous thrombosis is a rare condition. Its diagnosis and management can be difficult. Treatment options include systemically delivered anticoagulation or thrombolysis. Intrasinus thrombolysis is an increasingly used intervention but it increases the risk of hemorrhage, especially in patients who have a rapidly deteriorating neurological condition. Mechanical thrombectomy that provides rapid canalization without increased risk of hemorrhage is an attractive alternative treatment.

Methods: We describe the use of AngioJet rheolytic thrombectomy in 4 patients with extensive cerebral venous sinus thrombosis, preexisting intracranial hemorrhage, and severe progressive neurological deficit despite heparin therapy.

Results: Partial or complete sinus patency was restored in all 4 patients and complete neurological recovery was achieved in 3 patients.

Conclusion: Intracranial hemorrhage or a rapidly deteriorating neurological condition may preclude the use of thrombolytic agents in the treatment of patients with cerebral venous sinus thrombosis. In such patients, mechanical thrombectomy offers a useful alternative.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Aged, 80 and over
  • Anticoagulants / therapeutic use
  • Black or African American
  • Brain / blood supply
  • Brain / pathology
  • Brain / surgery
  • Dura Mater / blood supply*
  • Dura Mater / pathology
  • Dura Mater / surgery*
  • Female
  • Heparin / therapeutic use
  • Humans
  • Intracranial Hemorrhages / drug therapy
  • Intracranial Hemorrhages / pathology
  • Intracranial Hemorrhages / surgery
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neurosurgical Procedures
  • Phlebography
  • Sinus Thrombosis, Intracranial / drug therapy
  • Sinus Thrombosis, Intracranial / pathology
  • Sinus Thrombosis, Intracranial / surgery*
  • Thrombectomy*
  • Treatment Outcome
  • United States
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / pathology
  • Venous Thrombosis / surgery*
  • White People


  • Anticoagulants
  • Heparin