Abstract
A new disaccharoside (2) together with a known disaccharose (1) was isolated from the ethanol extract of Camptosorus sibiricus Rupr. By means of chemical (hydrolysis) and spectroscopic methods (IR, 1D and 2D NMR, ESI-MS), the structures were established as beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranoside (1) and Octane-1-en-3-ol-3-O-beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranoside (2) respectively. Compounds 1 and 2 were isolated from this genus first and their anti-tumour activities were tested against two human tumour cell lines using MTT method.
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Disaccharides / chemistry
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Disaccharides / isolation & purification*
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Disaccharides / pharmacology
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Ferns / chemistry*
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HeLa Cells
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Humans
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Molecular Structure
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Paclitaxel / pharmacology
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Plants, Medicinal / chemistry*
Substances
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Antineoplastic Agents, Phytogenic
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Disaccharides
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Drugs, Chinese Herbal
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octane-1-en-3-ol-3-O-beta-D-glucopyranosyl (1-2)-beta-D-glucopyranoside
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Paclitaxel