Licorice preparations improve efficiency of chemotherapy and surgical treatment of transplanted tumors
- PMID: 19023982
- DOI: 10.1007/s10517-008-0063-0
Licorice preparations improve efficiency of chemotherapy and surgical treatment of transplanted tumors
Abstract
Experiments on animals with Lewis lung carcinoma and Ehrlich tumor showed that licorice (glycyrrhiza) extract and glyciram prepared from this plant improved the antitumor effect of cyclophosphamide. Glyciram reduced the toxic effect of the cytostatic on peripheral blood leukocytes. Licorice extract inhibited the growth of Ehrlich tumor and development of metastases in mice with Lewis lung carcinoma. Glyciram administered to mice after removal of Lewis lung carcinoma produced an antimetastatic effect and prevented relapses.
Similar articles
-
Non-starch polysaccharides as correctors in cytostatic therapy of experimental tumors.Bull Exp Biol Med. 2006 Sep;142(3):351-5. doi: 10.1007/s10517-006-0364-0. Bull Exp Biol Med. 2006. PMID: 17426847 English, Russian.
-
[Medicinal plant preparations used as adjuvant therapeutics in experimental oncology].Eksp Klin Farmakol. 2000 Sep-Oct;63(5):59-61. Eksp Klin Farmakol. 2000. PMID: 11109531 Russian.
-
[Glyciram as an enhancer of the effectiveness of chemotherapy and surgery in the treatment of experimental neoplasms].Vopr Onkol. 1999;45(5):554-6. Vopr Onkol. 1999. PMID: 10629717 Russian.
-
[Effect of exogenous DNA on the growth of transplantable tumors].Vopr Onkol. 2006;52(1):66-9. Vopr Onkol. 2006. PMID: 16715707 Russian.
-
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.Int J Toxicol. 2007;26 Suppl 2:79-112. doi: 10.1080/10915810701351228. Int J Toxicol. 2007. PMID: 17613133 Review.
Cited by
-
Ocoxin oral solution® as a complement to irinotecan chemotherapy in the metastatic progression of colorectal cancer to the liver.Oncol Lett. 2017 Jun;13(6):4002-4012. doi: 10.3892/ol.2017.6016. Epub 2017 Apr 10. Oncol Lett. 2017. PMID: 28599406 Free PMC article.
-
Ocoxin® oral solution slows down tumor growth in an experimental model of colorectal cancer metastasis to the liver in Balb/c mice.Oncol Rep. 2016 Mar;35(3):1265-72. doi: 10.3892/or.2015.4486. Epub 2015 Dec 16. Oncol Rep. 2016. PMID: 26676882 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
