Abstract
In this issue of Molecular Cell, Kimata et al. (2008) show that Cdc20 functions not only in the recruitment of substrates to the anaphase-promoting complex but also in its activation.
MeSH terms
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Anaphase-Promoting Complex-Cyclosome
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Animals
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Cadherins / metabolism
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Cdc20 Proteins
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Cell Cycle Proteins / chemistry
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Cell Cycle Proteins / genetics
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Cell Cycle Proteins / metabolism*
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Protein Binding
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Protein Serine-Threonine Kinases / metabolism
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Protein Structure, Tertiary
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Substrate Specificity
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Ubiquitin-Protein Ligase Complexes / metabolism*
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Ubiquitination
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Xenopus / genetics
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Xenopus / metabolism
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Xenopus Proteins / chemistry
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Xenopus Proteins / genetics
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Xenopus Proteins / metabolism*
Substances
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Cadherins
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Cdc20 Proteins
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Cdc20 protein, Xenopus
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Cell Cycle Proteins
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Xenopus Proteins
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Ubiquitin-Protein Ligase Complexes
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Anaphase-Promoting Complex-Cyclosome
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NEK2 protein, Xenopus
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Protein Serine-Threonine Kinases