8-Nitroguanosines as chemical probes of the protein S-guanylation

Chem Commun (Camb). 2008 Dec 7;(45):5984-6. doi: 10.1039/b810771h. Epub 2008 Oct 14.

Abstract

Azido- and fluoro- derivatives of 8-nitroguanosine were developed, and will contribute to the exploration of protein S-guanylation by endogenous nitrated nucleosides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cells, Cultured
  • Cyclic GMP / analogs & derivatives
  • Cyclic GMP / chemical synthesis
  • Cyclic GMP / chemistry
  • Cyclic GMP / pharmacology
  • Cysteine / chemistry
  • Cysteine / metabolism
  • Guanosine / analogs & derivatives*
  • Guanosine / chemical synthesis
  • Guanosine / chemistry
  • Humans
  • Molecular Structure
  • Nitro Compounds / chemical synthesis
  • Nitro Compounds / chemistry*
  • Protein Processing, Post-Translational*
  • Signal Transduction

Substances

  • 8-nitroguanosine
  • 8-nitroguanosine 3',5'-cyclic monophosphate
  • Nitro Compounds
  • Guanosine
  • Cyclic GMP
  • Cysteine