Impact of diabetes on maternal-fetal outcomes in Manitoba: Relationship with ethnic and environmental factors

Clin Invest Med. 2008 Dec 1;31(6):E338-45. doi: 10.25011/cim.v31i6.4919.


Purpose: To examine the impact of gestational diabetes mellitus (GDM) on maternal-fetal outcomes in Manitoba.

Methods: The rates of macrosomia, stillbirth, cesarean section (C/S) and shoulder dystocia (S/D) in 324,605 births in Manitoba during 1985-2004, and their relationships with diabetes and demographical factors were analyzed.

Results: The incidence of macrosomia, stillbirth, C/S and S/D were 15.3%, 0.57%, 16.0%, and 1.2%, respectively. The rates of macrosomia were elevated in mothers with GDM, type 2 DM (T2DM), rural living, First Nations (FN) status, or >or=35 years of age. Increased rates of stillbirth were associated with women with T2DM, FN status or >or=35 years, but not those with GDM. C/S and S/D were increased in women with GDM or T2DM. FN status in combination with GDM increased the risk of S/D.

Conclusions: GDM, T2DM, advanced maternal age, FN status or rural living affected pregnancy outcomes in Manitoba.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Birth Weight
  • Cesarean Section / statistics & numerical data
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes, Gestational / epidemiology*
  • Diabetes, Gestational / ethnology
  • Dystocia / epidemiology
  • Environment*
  • Female
  • Fetal Macrosomia / epidemiology
  • Humans
  • Incidence
  • Logistic Models
  • Manitoba / epidemiology
  • Pregnancy
  • Pregnancy Complications / epidemiology
  • Pregnancy Complications / ethnology
  • Pregnancy Outcome*
  • Retrospective Studies
  • Risk Factors
  • Rural Population / statistics & numerical data
  • Stillbirth / epidemiology
  • Urban Population / statistics & numerical data