Malignant syphilis with ocular involvement and organism-depleted lesions

Clin Infect Dis. 2009 Jan 1;48(1):83-5. doi: 10.1086/594127.


Diagnosis and treatment of syphilis are challenging because of the condition's diverse clinical symptoms, histopathological variance, and the lack of definite tests for treatment follow-up. We report a case of secondary pustular-ulcerative malignant syphilis with ocular involvement in a human immunodeficiency virus-infected patient. It was striking to find that ulcerative lesions can be highly organism depleted.

Publication types

  • Case Reports

MeSH terms

  • Eye Diseases / etiology*
  • Eye Diseases / microbiology
  • Eye Diseases / pathology
  • HIV Infections / complications
  • Humans
  • Male
  • Middle Aged
  • Syphilis / complications*
  • Syphilis / microbiology
  • Syphilis / pathology
  • Ulcer / microbiology