Low catechol-O-methyltransferase and 2-methoxyestradiol in preeclampsia: more than a unifying hypothesis

Nephrol Dial Transplant. 2009 Jan;24(1):31-3. doi: 10.1093/ndt/gfn534. Epub 2008 Nov 27.

Authors

Duska Dragun¹, Anja Haase-Fielitz

Affiliation

¹ Department of Nephrology and Intensive Care Medicine, Charité University Hospital, Berlin, Germany. duska.dragun@charite.de

PMID: 19039028
DOI: 10.1093/ndt/gfn534

No abstract available

Publication types

Review

MeSH terms

2-Methoxyestradiol
Animals
Catechol O-Methyltransferase / deficiency*
Catechol O-Methyltransferase / physiology
Endothelium, Vascular / physiopathology
Estradiol / analogs & derivatives*
Estradiol / biosynthesis
Estradiol / physiology
Female
Humans
Mice
Models, Biological
Neovascularization, Pathologic
Pre-Eclampsia / etiology*
Pre-Eclampsia / physiopathology
Pregnancy
Signal Transduction
Vascular Endothelial Growth Factor A / physiology
Vascular Endothelial Growth Factor Receptor-1 / physiology

Substances

Vascular Endothelial Growth Factor A
Estradiol
2-Methoxyestradiol
Catechol O-Methyltransferase
Vascular Endothelial Growth Factor Receptor-1