Hospital admissions for meningococcal infection in Spain (1997-2005)

J Infect. 2009 Jan;58(1):15-20. doi: 10.1016/j.jinf.2008.10.009. Epub 2008 Nov 30.


Objectives: Spanish hospital surveillance system was analyzed to estimate the burden of hospital admissions for meningococcal infection in Spain during a nine-year period (1997-2005).

Methods: Data were obtained from the national surveillance system for hospital data (Conjunto Mínimo Básico de Datos) maintained by the Ministry of Health and covering more than 95% of Spanish hospitals.

Results: There were 9480 hospital admissions for meningococcal infection (ICD 9 CM 036; any listed diagnosis) during the study period. Annual incidence was 2.66 cases per 100,000 population. Rate of death and case-fatality rate were 0.17 per 100,000 population and 6.45%, respectively. The average length of hospitalization was 11.2 days. Youngest age group showed the highest incidence and rate of death (43.15 and 1.17 per 100,000 population respectively in 0-4 years old group), but case-fatality rate was higher in the oldest group (12.16%; more than 30 years old group). The cost of acute hospital care is estimated to be on average 4470 euro per case, which imposes an annual direct cost of 3-5 million euro to the Spanish health system.

Conclusions: Meningococcal infection is still an important cause of hospital admissions in Spain and results in large cost to the Health Care System.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Hospitalization / economics
  • Hospitalization / statistics & numerical data*
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Length of Stay
  • Meningococcal Infections / economics
  • Meningococcal Infections / epidemiology*
  • Meningococcal Infections / mortality
  • Middle Aged
  • Spain / epidemiology
  • Young Adult